肝微粒體是體外研究一個化合物的代謝(酶抑制,清除率和代謝鑒定)以及藥物-藥物相互作用的主要工具。通常根據特定細胞色素酶的活性水平來選擇微粒體。
齊氏生物提供的肝細胞微粒體,每批產品都經過嚴格的制備、檢測,確保批次間穩定性,然后于凍存管包裝,10 mg/管;-80℃保存,干冰運輸。
用途:ADME及藥代動力學檢測試驗
種屬:人/大鼠/小鼠/兔/狗/豬/猴 /牛
規格:0.5ml 20mg/ml
運輸:凍存管,干冰運輸。
微粒體產品被SCI論文引用(部分):
1.Metabolism of chicoric acid by rat liver microsomes and bioactivity comparisons of chicoric acid and its metabolites
Q Liu, Y Wang, CX Xiao, W Wu, X Liu - Food & function, 2015 - pubs.rsc.org
… 11–14 Moreover, chicoric acid has showed anti-inflammatory, anti-bacterial, anti-HIV
activities, hypoglycemic and hepatocyte protective properties …
Rat liver microsomes
were obtained from
CHI Scientific, Inc. (Massachusetts, USA)
文章鏈接:
https://doi.org/10.1039/C5FO00073D
2.
Hypoxia-triggered gene therapy: a new drug delivery system to utilize photodynamic-induced hypoxia for synergistic cancer therapy
C Huang, J Zheng, D Ma, N Liu, C Zhu, J Li… - Journal of Materials …, 2018 - pubs.rsc.org
…
Rat liver microsomes were purchased from
CHI Scientific (Jiangsu China … under hypoxic conditions
(red curve); DDS in the presence of inactive rat liver microsomes and NADPH … 0 represent the
fluorescence intensity of TAMRA after and before rat liver microsome addition under …
文章鏈接:
https://doi.org/10.1039/C8TB01805G
附:產品介紹

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