Synonyms :
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TNF-related weak inducer of apoptosis receptor, TNFRSF12A, FGF-inducible 14
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Description :
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TWEAKR belongs to the TNF family of transmembrane proteins and contains a cytoplasmic "death domain", which can activated the cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein.
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Catalog #:
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310-21
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Source :
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E.coli
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Purity :
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Greater than 98% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Biological Activity :
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Determined by its ability to inhibit TWEAK-induced weak cell death of HT29 cells. The expected ED
50
for this effect is 1.0-3.0 µg/ml.
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AA Sequence :
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EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP
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PubMed Link :
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Tweak+AND+TNF+AND+receptor
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Country of Origin :
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USA
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| Size A
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5µg
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$80
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| Size B
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25µg
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$195
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| Size C
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1mg
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$3000
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Special Sizes:
Many products can be ordered in custom sizes. Please click here
to contact with your request.
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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