Synonyms :
|
none.
|
Description :
|
IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.
|
Catalog #:
|
200-20
|
Source :
|
E.coli
|
Purity :
|
Greater than 98% by SDS-PAGE gel and HPLC analyses.
|
Endotoxin Level :
|
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
|
Biological Activity :
|
Determined by its ability to activate STAT following receptor ligand interaction.
|
Selected References :
|
Selected List of References Citing This Product
|
AA Sequence :
|
MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE
|
PubMed Link :
|
IL-20+AND+interleukin+AND+human
|
Country of Origin :
|
USA
|
|
|
|
|
| Size A
|
2µg
|
$80
|
|
| |
| Size B
|
10µg
|
$195
|
|
| |
| Size C
|
1mg
|
$5200
|
|
| |
|
|
|
|
Special Sizes:
Many products can be ordered in custom sizes. Please click here
to contact with your request.
|
|
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
|
