Synonyms :
|
None
|
Description :
|
Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
|
Catalog #:
|
120-14E
|
Source :
|
E.coli
|
Purity :
|
Greater than 97% by SDS-PAGE gel and HPLC analyses.
|
Endotoxin Level :
|
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
|
Biological Activity :
|
The ED
50
as determined by its ability to inhibit the proliferation of murine MPC-11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105
units/mg.
|
AA Sequence :
|
GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
|
PubMed Link :
|
Activin+AND+A+AND+human
|
Country of Origin :
|
USA
|
|
|
|
|
| Size A
|
2µg
|
$80
|
|
| |
| Size B
|
10µg
|
$195
|
|
| |
| Size C
|
1mg
|
$5200
|
|
| |
|
|
|
|
Special Sizes:
Many products can be ordered in custom sizes. Please click here
to contact with your request.
|
|
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
|
