Synonyms :
|
EDF, BCDFII, TRF
|
Description :
|
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant human IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.
|
Catalog #:
|
200-05
|
Source :
|
E.coli
|
Purity :
|
Greater than 98% by SDS-PAGE gel and HPLC analyses.
|
Endotoxin Level :
|
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
|
Biological Activity :
|
The ED
50
as determined by the dose-dependent proliferation of TF-1 cells was ≤ 0.15 ng/ml, corresponding to a specific activity of ≥ 6.6 x 106
units/mg.
|
Selected References :
|
Selected List of References Citing This Product
|
AA Sequence :
|
MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES
|
PubMed Link :
|
IL-5
|
Country of Origin :
|
USA
|
|
|
|
Size A
|
2µg
|
$80
|
|
|
Size B
|
10µg
|
$195
|
|
|
Size C
|
1mg
|
$4300
|
|
|
|
|
|
|
Special Sizes:
Many products can be ordered in custom sizes. Please click here
to contact with your request.
|
|
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
|