Synonyms :
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IL-29
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Description :
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IFN λ-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas use a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. (Kotenko, SV. et al. Nat Immunology
2003 [1] p. 69-77). Recombinant human IFN-λ 1 is a 19.8 kDa protein containing 178 amino acid residues.
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Catalog #:
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300-02L
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Source :
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E.coli
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Purity :
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Greater than 98% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Biological Activity :
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Recombinant human IFN-lambda 1 induces phosphorylation of STAT2.
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Selected References :
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Selected List of References Citing This Product
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AA Sequence :
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PTSKPTTTGK GCHIGRFKSL SPQELASFKK ARDALEESLK LKNWSCSSPV FPGNWDLRLL QVRERPVALE AELALTLKVL EAAAGPALED VLDQPLHTLH HILSQLQACI QPQPTAGPRP RGRLHHWLHR LQEAPKKESA GCLEASVTFN LFRLLTRDLK YVADGNLCLR TSTHPEST
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PubMed Link :
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IFN-lambda-1+OR+IL-29
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Country of Origin :
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USA
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Size A
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5µg
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$80
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Size B
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20µg
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$195
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Size C
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1mg
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$3000
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Special Sizes:
Many products can be ordered in custom sizes. Please click here
to contact with your request.
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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