Synonyms :
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Trefoil Factor 2, Spasmolytic polypeptide (SP), Spasmolysin
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Description :
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The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma (Nikolaidis, N.M. et al. Am. Journal Respir. Cell Mol. Biol. (2003) 4: 458-464
). Recombinant human TFF2 is a 12.0 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
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Catalog #:
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300-59
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Source :
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E.coli
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Purity :
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Greater than 98% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Biological Activity :
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Assay #1:
Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 µg/ml.
Assay #2:
Determined by its ability to chemoattract human MCF-7 cells using a concentration range of 1.0-10.0 ng/ml.
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Selected References :
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Selected List of References Citing This Product
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AA Sequence :
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EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
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PubMed Link :
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TFF-2+OR+TFF2
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Country of Origin :
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USA
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| Size A
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5µg
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$80
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| Size B
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20µg
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$195
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| Size C
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1mg
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$3000
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Special Sizes:
Many products can be ordered in custom sizes. Please click here
to contact with your request.
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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