Synonyms :
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FIZZ3, Adipose tissue-specific secretory factor, ADSF
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Description :
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Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant murine Resistin is a 20.2 kDa disulfide-linked homodimeric protein composed of two identical 94 amino acid chains linked by a single disulfide bond.
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Catalog #:
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450-28
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Source :
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E.coli
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Purity :
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Greater than 98% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Biological Activity :
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Not available at this time.
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Selected References :
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Selected List of References Citing This Product
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AA Sequence :
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SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLASCPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL QVAS
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PubMed Link :
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Resistin+AND+mouse
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Country of Origin :
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USA
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| Size A
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5µg
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$80
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| Size B
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25µg
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$195
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| Size C
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1mg
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$5200
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Special Sizes:
Many products can be ordered in custom sizes. Please click here
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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