Synonyms :
|
Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF
|
Description :
|
FGF-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF8 A and B are identical unlike human and mouse FGF8 E and F are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant human FGF-8 (FGF-8b) is a 22.4 kDa protein consisting of 193 amino acid residues.
|
Catalog #:
|
100-25
|
Source :
|
E.coli
|
Purity :
|
Greater than 95% by SDS-PAGE gel and HPLC analyses.
|
Endotoxin Level :
|
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
|
Biological Activity :
|
The ED
50
as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106
units/mg.
|
Selected References :
|
Selected List of References Citing This Product
|
AA Sequence :
|
MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR
|
PubMed Link :
|
FGF-8
|
Country of Origin :
|
USA
|
|
|
|
|
| Size A
|
5µg
|
$80
|
|
| |
| Size B
|
25µg
|
$195
|
|
| |
| Size C
|
1mg
|
$3000
|
|
| |
|
|
|
|
Special Sizes:
Many products can be ordered in custom sizes. Please click here
to contact with your request.
|
|
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
|
