Synonyms :
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p40 cytokine, T-cell growth factor p40
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Description :
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IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant murine IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.
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Catalog #:
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219-19
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Source :
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E.coli
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Purity :
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Greater than 98% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Biological Activity :
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The ED50
as determined by the dose-dependent proliferation of human MO7e cells is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 106
units/mg.
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Selected References :
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Selected List of References Citing This Product
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AA Sequence :
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MQRCSTTWGI RDTNYLIENL KDDPPSKCSC SGNVTSCLCL SVPTDDCTTP CYREGLLQLT NATQKSRLLP VFHRVKRIVE VLKNITCPSF SCEKPCNQTM AGNTMSFLKS LLGTFQKTEM QRQKSRP
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PubMed Link :
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IL-9+AND+mouse
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Country of Origin :
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USA
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| Size A
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2µg
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$80
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| Size B
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10µg
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$195
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| Size C
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1mg
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$5200
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Special Sizes:
Many products can be ordered in custom sizes. Please click here
to contact with your request.
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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