Synonyms :
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CCL11
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Description :
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Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-gamma stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and along Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung, and in allergic reactions. Recombinant murine Eotaxin is an 8.4 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
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Catalog #:
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250-01
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Source :
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E.coli
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Purity :
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Greater than 98% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Biological Activity :
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Murine Eotaxin was found to induce chemotaxis of purified eosinophils at concentrations ranging between 100-1000 ng/ml.
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Selected References :
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Selected List of References Citing This Product
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AA Sequence :
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HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP
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PubMed Link :
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eotaxin+AND+mouse
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Country of Origin :
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USA
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| Size A
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5µg
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$80
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| Size B
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20µg
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$195
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| Size C
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1mg
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$3000
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Special Sizes:
Many products can be ordered in custom sizes. Please click here
to contact with your request.
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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